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| Presentation |
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"Thyroid"Dr. Mark Sherman (biography)
English - 2005-08-14 - 30 minutes
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Summary :
In this presentation Dr. Sherman discusses guidelines for subclinical thyroid disease and topics relating to medications and thyroid function.
In 2004, a scientific review and guidelines for diagnosis and management of subclinical thyroid disease was published by Surks et al., recommending against routine treatment of patients with TSH levels in the ranges of 0.1 to 0.45 mIU/L or 4.5 to 10 mIU/L (1). Dr. Sherman discusses these recommendations and some of the controversy surrounding them.
With regards to medications and thyroid function, Dr. Sherman reviews some recent findings relating to amiodarone-induced thyroid dysfunction (2), hypothyroidism due to ethionamide (3), central hypothyroidism with bexarotene (4), and finally an update on combined T4/T3 treatment for hypothyroidism (5).
Copyright © 2006 E-MedHosting.com Inc.
Learning objectives :
After viewing this presentation the participant will be able to discuss:
- Subclinical thyroid disease guidelines
- Effects of medications on thyroid function
- Combined T4/T3 treatment for hypothyroidism
Bibliographic references :
1. Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, Franklyn JA, Hershman JM, Burman KD, Denke MA, Gorman C, Cooper RS, Weissman NJ.Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA. 2004 Jan 14;291(2):228-38.
2. Shehzad Basaria MD and David S. Cooper MD. Amiodarone and the thyroid Am J Med. 2005 Jul;118(7):706-14.
3. McDonnell ME et al. N Engl J Med. 2005 Jun 30;352(26):2757-9.
4. Steven I. Sherman, M.D., Jayashree Gopal, M.D., Bryan R. Haugen, M.D., Alice C. Chiu, M.D., Kevin Whaley, M.D., Prem Nowlakha, M.D., and Madeleine Duvic, M.D. Central Hypothyroidism Associated with Retinoid X Receptor–Selective Ligands N Engl J Med. 1999 Apr 8;340(14):1075-9.
5. Rodriguez T, Lavis VR, Meininger JC, Kapadia AS, Stafford LF. Substitution of liothyronine at a 1:5 ratio for a portion of levothyroxine: effect on fatigue, symptoms of depression, and working memory versus treatment with levothyroxine alone. Endocr Pract. 2005 Jul-Aug;11(4):223-33.
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