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- May 17, 2008 |
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"Should insulin resistance be considered a therapeutic target to slow or prevent macrovascular complications?"Dr. Steven V. Edelman (biography)
English - 2004-06-04 - 12 minutes
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Summary :
Numerous cardiovascular risk factors are associated with insulin resistance, which can be improved with the thiazolidinedione class of drugs. Also, impaired glucose tolerance has been shown to increase CHD mortality risk, therefore the identification of these patients is important.
Copyright © 2004 E-MedHosting.com Inc.
Learning objectives :
After viewing these slides the participant will be able to discuss:
- The cardiovascular risk factors associated with insulin resistance
- Metabolic effects of oral antidiabetic agents
- Atherosclerosis therapy in type 2 diabetes
- The relationship between CHD risk factors and glucose tolerance
Bibliographic references :
Joshua A. Beckman, MD,MS; Mark A. Creager, MD; Peter Libby, MD. Diabetes and Atherosclerosis: Epidemiology, Pathophysiology, and Management JAMA. 2002;287:2570-2581.
Eschwege E, Richard JL, Thibult N, Ducimetiere P, Warnet JM, Claude JR, Rosselin GE.Coronary heart disease mortality in relation with diabetes, blood glucose and plasma insulin levels. The Paris Prospective Study, ten years later. Horm Metab Res Suppl. 1985;15:41-6.
Samy I. McFarlane, Maryann Banerji and James R. Sowers. Insulin Resistance and Cardiovascular Disease The Journal of Clinical Endocrinology & Metabolism 2001;82(2):713-718.
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