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- May 12, 2008 |
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Welcome to the #1 online source of information for Diabetes Specialists! An international online community of more than 10,000 Diabetes Specialists.
CME on Diabetes is a website built to transmit top-level CME conferences given by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome and type 2 diabetes. More than 2.6 million slides have been viewed since the website launch. Thank you for your continued support and commitment!
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"PROactive"Prof. Markolf Hanefeld (biography)
English - 2005-04-16 - 33 minutes
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Summary :
Prof. Hanefeld presents the pleiotropic effects of pioglitazone such as on insulin sensitivity, glucose tolerance, lipid levels, HbA1c, etc. Of interest is the effect of pioglitazone on vascular function. Prof. Hanefeld discusses data supporting the positive effect of pioglitazone on coronary blood flow, atherosclerosis, plaque formation, smooth muscle cells, and left ventricular hypertrophy.
The PioglitAzone Clinical Trial In MacroVascular Events Study (ProActive) aims to demonstrate the safety and efficacy of pioglitazone in reducing macrovascular morbidity in high-risk patients with type 2 diabetes. Prof. Hanefeld, presents the study objective and some preliminary results here in detail.
Copyright © 2005 E-MedHosting.com Inc.
Learning objectives :
After viewing this presentation, participants will be able to discuss:
- The pleiotropic effects of pioglitazone;
- The PROactive study;
- Further secondary objectives of the proactive study.
Bibliographic references :
Bo Isomaa, Peter Almgren, Tiinamaija Tuomi, Björn Forsén, Kaj Lahti, Michael Nissén, Marja-Riitta Taskinen, and Leif Groop Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome Diabetes Care 24: 683-689
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