 |
|
 |
- May 12, 2008 |
|
|
Welcome to the #1 online source of information for Diabetes Specialists! An international online community of more than 10,000 Diabetes Specialists.
CME on Diabetes is a website built to transmit top-level CME conferences given by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome and type 2 diabetes. More than 2.6 million slides have been viewed since the website launch. Thank you for your continued support and commitment!
|
|
|
| Presentation |
|
"Managing the 21st Century Diabetes Epidemic: Treatment and Prevention"Dr. David M. Nathan (biography)
English - 2003-06-14 - 50 minutes
|
 | (48 slides) |
Summary :
In this presentation we will discuss new findings from the DPP presented at the Recent Data from type 2 Diabetes Clinical Trials Symposium at the 63rd ADA Meeting in New Orleans. We will look at our ability to treat diabetes and prevent complications, the limitations of our current means of doing so, and our ability to prevent diabetes. We saw from the UKPDS that stepped treatment resulted in a steady rise in HbA1c, and we now realise that a combination therapy involving drugs with different mechanisms tends to result in a more synergistic and additive effect of the drugs. Intensive lifestyle interventions were found to have a great effect in reducing the incidence of diabetes, and in lowering some risk factors. Metformin was also found to reduce some CVD risk factors, and was found to have some contribution in the prevention of diabetes as well.
Learning objectives :
- The U.S. sees 800,000 new type 2 diabetes cases per year.
- Combination therapies involving drugs with different mechanisms of action tend to produce more synergistic and additive effects.
- The DPP found lifestyle to have the greatest effect in lowering the incidence of diabetes, followed by metformin and then placebo.
- Weight loss was the most important mediator of lifestyle related Diabetes prevention.
- Conventional risk factors such as BP and triglyceride levels were improved by intensive lifestyle but not by metformin.
- Indices of inflammation and hemorheologic disorders were generally improved with lifestyle, and some factors like TPA and CRP (in women) were also improved by metformin.
- IGT and IFG have been renamed ''pre-diabetes''.
Bibliographic references :
http://www.ncbi.nlm.nih.gov
Goldhaber-Fiebert JD, Goldhaber-Fiebert SN, Tristan ML, Nathan DM.
Randomized controlled community-based nutrition and exercise intervention
improves glycemia and cardiovascular risk factors in type 2 diabetic
patients in rural costa rica.
Diabetes Care. 2003 Jan;26(1):24-9.
|
|
|
|
|
|
| Search our website |
 |
| |
Would you like to know more about insulin resistance? Are you looking for information pertaining to Type 2 Diabetes? You can find what you are looking for in over 2000 references available on CMEonDiabetes. |
| |
|
|
| Social |
|
| |
Let others know about this presentation.
|
|
|
|
