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- July 4, 2008 |
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"Epidemiology of Prediabetes and Metabolic Syndrome in Indians"Dr. A. Ramachandran (biography)
English - 2005-04-14 - 25 minutes
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Summary :
Objective: To highlight high prevalence and the peculiarities of prediabetic conditions and the metabolic syndrome in India.
Method: Epidemiological data on the prevalence and risk associations of prediabetic conditions, and occurrence and peculiarities in metabolic syndrome are described.
Results: Both IFG (8.7%) and IGT (8.1%) show high prevalence in India with an overlap in one-third. Prevalence of IGT is high in urban and rural areas. A potential rise in diabetes is indicated by an IGT to diabetes ratio > 1. IGT was very common at all ages, the prevalence in <40 and 40 years did not differ much. Diabetes was higher in older groups. In < 40 year group, IGT was seen in 13.1% versus 5% of diabetes. In the > 40 years group, diabetes was more common (24%) than IGT (15.7%). The risk associations with anthropometric variables and with family history of diabetes were also different in these groups. IFG had a higher insulin resistance than IGT and was also associated with cell defect. Metabolic syndrome is highly prevalent among urban Indians (41.1 %). Its prevalence increased with age and was higher among women. Clustering of cardiovascular risk factors are common in IGT and IFG; therefore it carries a high risk of CVD. Insulin resistance is a major component of the cluster, but it is not an integral part of all the clusters in the syndrome.
Conclusions: High prevalence of IGT, IFG and the metabolic syndrome predict a major burden from diabetes and CVD in India.
Learning objectives :
After viewing this presentation, participants will be able to discuss:
• The prevalence of prediabetes in the Indian population based on IGT and IFG;
• The prevalence of the metabolic syndrome among the Indian population.
Bibliographic references :
Ramachandran A, Snehalatha C, Vijay V.Temporal changes in prevalence of type 2 diabetes and impaired glucose tolerance in urban southern India.Diabetes Res Clin Pract. 2002 Oct;58(1):55-60
Ramachandran A, Snehalatha C, Kapur A, Vijay V, Mohan V, Das AK, Rao PV, Yajnik CS, Prasanna Kumar KM, Nair JD; Diabetes Epidemiology Study Group in India (DESI).High prevalence of diabetes and impaired glucose tolerance in India: National Urban Diabetes Survey.Diabetologia. 2001 Sep;44(9):1094-101.
Ramachandran A, Snehalatha C, Baskar AD, Mary S, Kumar CK, Selvam S, Catherine S, Vijay V.Temporal changes in prevalence of diabetes and impaired glucose tolerance associated with lifestyle transition occurring in the rural population in India.Diabetologia. 2004 May;47(5):860-5. Epub 2004 Apr 28.
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