 |
|
 |
- July 4, 2008 |
|
|
Welcome to the #1 online source of information for Diabetes Specialists! An international online community of more than 10,000 Diabetes Specialists.
CME on Diabetes is a website built to transmit top-level CME conferences given by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome and type 2 diabetes. More than 2.6 million slides have been viewed since the website launch. Thank you for your continued support and commitment!
|
|
|
| Presentation |
|
"Beta Cell Failure in type 2 Diabetes: A Paradigm Revisited"Dr. Minna Woo (biography)
English - 2002-01-19 - 20 minutes
|
 | (20 slides) |
Summary :
Pathology of type 2 diabetes is a combination of insulin resistance and defective beta-cells. Overview of the impact of b cells in this pathology and a conclusion that demonstrates that a change in the cellular function and mass of beta-cells are both involved in the development of type 2 diabetes.
Learning objectives :
Upon completion of this presentation, participants should be able to understand the:
1.Importance of b cell failure in the development and progression of Type 2 DM.
2.Potential causes of b cell failure.
3.Mechanisms of b cell failure.
Bibliographic references :
Executionary pathway for apoptosis: lessons from mutant mice.
Woo M, Hakem R, Mak TW.
Amgen Institute and Ontario Cancer Institute, Department of Immunology, University of Toronto, Canada. mwoo@oci.utoronto.ca
Apoptosis or programmed cell death (PCD) is an evolutionarily conserved cellular process that is essential for normal development and homeostasis of multicellular organisms. Defects in the apoptosis signaling result in many diseases including autoimmune diseases and cancer. The apoptosis signaling pathway was first described genetically in the nematode Caenorhabditis elegans which serves as a framework for the more complex apoptotic pathways that exist in mammals. In this review, we will discuss the apoptotic pathways that are emerging in mammals as elucidated by studies of gene-targeted mutant mice.
Cell Res 2000 Dec;10(4):267-78
|
|
|
|
|
|
| Search our website |
 |
| |
Would you like to know more about insulin resistance? Are you looking for information pertaining to Type 2 Diabetes? You can find what you are looking for in over 2000 references available on CMEonDiabetes. |
| |
|
|
| Social |
|
| |
Let others know about this presentation.
|
|
|
|
